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- 抗原 See all KCNMB1 抗体
- KCNMB1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNMB1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of MaxiKbeta protein. (region surrounding Lys119)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- Affinity chromatography
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product KCNMB1 Primary Antibody
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anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) antibody
KCNMB1 适用: 人, 小鼠, 大鼠 ELISA, WB, IF, ICC, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) (Center) antibodyKCNMB1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) (AA 40-130) antibodyKCNMB1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) antibodyKCNMB1 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) (AA 30-102) antibodyKCNMB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- KCNMB1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1))
- 别名
- KCNMB1 (KCNMB1 产品)
- 别名
- KCNMB1 antibody, BKbeta1 antibody, K(VCA)beta antibody, SLO-BETA antibody, hbeta1 antibody, hslo-beta antibody, k(VCA)beta-1 antibody, slo-beta-1 antibody, BKBETA antibody, potassium calcium-activated channel subfamily M regulatory beta subunit 1 antibody, potassium large conductance calcium-activated channel, subfamily M, beta member 1 antibody, KCNMB1 antibody, Kcnmb1 antibody
- 背景
- The KCNMB1 gene, located on chromosome 5q34, contains four exons and encodes the 191 amino-acid protein MaxiKbeta subunit 1 (also designated calcium-activated potassium channel beta subunit, BK channel beta subunit, Slo-beta and KVCAbeta). MaxiKbeta subunit 1 consists of two putative transmembrane domains, an extracellular loop containing three consensus sequences for N-linked glycosylation and four cysteine residues that might form disulfide bridges. MaxiKbeta subunit 1, one of four subunits in the MaxiKbeta family, is expressed predominately in smooth muscle tissue but is also found in brain, liver and lymphatic tissues. MaxiKbeta subunit 1 associates with MaxiKalpha to form a calcium-activated potassium channel (also designated MaxiK and BK channel). MaxiKbeta subunit 1 increases the sensitivity of the MaxiKalpha to calcium and voltage. The MaxiKalpha/beta1 channel is the most sensitive of all Maxi channels to calcium. MaxiKbeta plays an important role in vasoregulation by controlling the sensitivity of MaxiK channels to calcium, which leads to the proper amount of arterial relaxation.Synonyms: BK channel beta-1, Calcium-activated potassium channel subunit beta-1, Charybdotoxin receptor subunit beta-1, K VCAbeta-1, Maxi K channel beta-1, Slo-beta-1, subfamily M beta-1
- 分子量
- approx. 30 kDa
- 基因ID
- 3779
- NCBI登录号
- NP_004128
- UniProt
- Q16558
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