KCNMB1 抗体 (AA 40-130)
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- 抗原 See all KCNMB1 抗体
- KCNMB1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1))
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抗原表位
- AA 40-130
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNMB1 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Calcium-activated potassium channel subunit beta-1 protein (40-130AA)
- 亚型
- IgG
- Top Product
- Discover our top product KCNMB1 Primary Antibody
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- 应用备注
- Recommended dilution: IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- KCNMB1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1))
- 别名
- KCNMB1 (KCNMB1 产品)
- 别名
- KCNMB1 antibody, BKbeta1 antibody, K(VCA)beta antibody, SLO-BETA antibody, hbeta1 antibody, hslo-beta antibody, k(VCA)beta-1 antibody, slo-beta-1 antibody, BKBETA antibody, potassium calcium-activated channel subfamily M regulatory beta subunit 1 antibody, potassium large conductance calcium-activated channel, subfamily M, beta member 1 antibody, KCNMB1 antibody, Kcnmb1 antibody
- 背景
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Background: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Increases the apparent Ca(2+)/voltage sensitivity of the KCNMA1 channel. It also modifies KCNMA1 channel kinetics and alters its pharmacological properties. It slows down the activation and the deactivation kinetics of the channel. Acts as a negative regulator of smooth muscle contraction by enhancing the calcium sensitivity to KCNMA1. Its presence is also a requirement for internal binding of the KCNMA1 channel opener dehydrosoyasaponin I (DHS-1) triterpene glycoside and for external binding of the agonist hormone 17-beta-estradiol (E2). Increases the binding activity of charybdotoxin (CTX) toxin to KCNMA1 peptide blocker by increasing the CTX association rate and decreasing the dissociation rate.
Aliases: BK channel beta subunit antibody, BK channel subunit beta 1 antibody, BK channel subunit beta-1 antibody, BKbeta antibody, BKbeta1 antibody, Calcium activated potassium channel subfamily M subunit beta 1 antibody, Calcium activated potassium channel subunit beta 1 antibody, Calcium activated potassium channel subunit beta antibody, Calcium-activated potassium channel antibody, Calcium-activated potassium channel subunit beta antibody, Calcium-activated potassium channel subunit beta-1 antibody, Charybdotoxin receptor subunit beta 1 antibody, Charybdotoxin receptor subunit beta-1 antibody, Hbeta1 antibody, hslo beta antibody, K(VCA)beta 1 antibody, K(VCA)beta antibody, K(VCA)beta-1 antibody, KCMB1_HUMAN antibody, KCNMB 1 antibody, Kcnmb1 antibody, Large conductance Ca2+ activated K+ channel beta 1 subunit antibody, Maxi K channel beta subunit antibody, Maxi K channel subunit beta 1 antibody, Maxi K channel subunit beta-1 antibody, Potassium large conductance calcium activated channel subfamily M beta member 1 antibody, Slo beta 1 antibody, SLO beta antibody, Slo-beta antibody, Slo-beta-1 antibody, subfamily M subunit beta-1 antibody
- UniProt
- Q16558
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