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- 抗原 See all CXCL12 抗体
- CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CXCL12 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of SDF-1 protein. Species Reactivity: Tested: Human, Mouse and Rat.
- 纯化方法
- Affinity Chromatography using epitope-specific immunogen
- Top Product
- Discover our top product CXCL12 Primary Antibody
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anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) antibody
CXCL12 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 23-89) antibodyCXCL12 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 22-89) antibodyCXCL12 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 31-80) antibodyCXCL12 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 22-89) antibodyCXCL12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (C-Term) antibodyCXCL12 适用: 人, 小鼠, 犬, 小鸡, 非洲爪蟾, Bat, 豚鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) antibodyCXCL12 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 24-70) antibodyCXCL12 适用: 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (C-Term) antibodyCXCL12 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Ligand 12 (CXCL12) (AA 23-89) antibodyCXCL12 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
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- 应用备注
- Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH~7.2 0.05% Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- 有效期
- 12 months
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- 抗原
- CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
- 别名
- CXCL12 / SDF1 (CXCL12 产品)
- 别名
- IRH antibody, PBSF antibody, SCYB12 antibody, SDF1 antibody, TLSF antibody, TPAR1 antibody, CINC-1 antibody, Gro1 antibody, Pbsf antibody, Scyb12 antibody, Sdf1 antibody, Tlsf antibody, Tpar1 antibody, Fsp antibody, KC antibody, Mgsa antibody, N51 antibody, Scyb1 antibody, gro antibody, sdf-1 antibody, sdf1 antibody, xSDF-1 antibody, SDF-1 antibody, cxcl12 antibody, sdf-1a antibody, sdf1a antibody, wu:fa55e10 antibody, wu:fc16h12 antibody, wu:fj84c02 antibody, C-X-C motif chemokine ligand 12 antibody, C-X-C motif chemokine ligand 1 antibody, chemokine (C-X-C motif) ligand 12 antibody, chemokine (C-X-C motif) ligand 1 antibody, C-X-C motif chemokine ligand 12 L homeolog antibody, chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) antibody, CXCL12 antibody, cxcl12 antibody, Cxcl1 antibody, Cxcl12 antibody, cxcl12.L antibody, cxcl12a antibody
- 背景
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The C-X-C or alpha chemokine family is characterized by a pair of cysteine residues separated by a single amino acid and primarily functions as chemoattractants for neutrophils. The C-X- C family includes IL-8, NAP-2, MSGA and stromal cell-derived factor-1, or SDF-1. SDF-1 was originally described as a pre-B cell stimulatory factor, but has now been shown to function as a potent chemoattractant for T cells and monocytes, but not neutrophils. Receptors for the C-X-C family are G protein-coupled, seven-pass, transmembrane domain proteins which include IL-8RA, IL-8RB and fusin (also designated LESTR or CXCR-4). Fusin is highly homologous to the IL-8 receptors, sharing 37% sequence identity at the amino acid level. The IL-8 receptors bind to IL-8, NAP-2 and MSGA, while fusin binds to its cognate ligand, SDF-1. Fusin has been identified as the major co-receptor for T-tropic HIV-1, and SDF-1 has been shown to inhibit HIV-1 infection. Six human SDF-1 isoforms exist due to alternative splicing of CXCL12, the gene encoding SDF-1. Three isoforms are known for mouse and rat.
Alternate names: C-X-C motif chemokine 12, IRH, Intercrine reduced in hepatomas, PBSF, Pre-B cell growth- stimulating factor, SDF1A, SDF1B, Stromal cell-derived factor 1, hIRH - 基因ID
- 6387
- NCBI登录号
- NP_000600
- UniProt
- P48061
- 途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling
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