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HIF3A 抗体

HIF3A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498504
发货至: 中国
  • 抗原 See all HIF3A 抗体
    HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
    适用
    • 29
    • 16
    • 13
    • 1
    人, 小鼠, 大鼠
    宿主
    • 27
    • 4
    • 1
    克隆类型
    • 31
    • 1
    多克隆
    标记
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HIF3A antibody is un-conjugated
    应用范围
    • 19
    • 11
    • 10
    • 5
    • 2
    • 2
    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of HIF-3alpha protein. (region surrounding Glu354)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product HIF3A Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
    别名
    HIF3A / HIF3 alpha (HIF3A 产品)
    别名
    HIF-3A antibody, IPAS antibody, MOP7 antibody, PASD7 antibody, bHLHe17 antibody, Ipas antibody, NEPAS antibody, Mop7 antibody, HIF3A antibody, hypoxia inducible factor 3 alpha subunit antibody, hypoxia inducible factor 3, alpha subunit antibody, HIF3A antibody, Hif3a antibody
    背景
    Cell growth and viability is compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1α, HIF-1β (also designated Arnt 1), EPAS-1 (also designated HIF-2α) and HIF-3α, induce glycolysis, erythropoiesis and angiogenesis in order to restore oxygen homeostasis. Hypoxia-inducible factors are members of the Per-Arnt-Sim (PAS) domain transcription factor family. In response to hypoxia, HIF-1α is upregulated and forms a heterodimer with Arnt 1 to form the HIF-1 complex. The HIF-1 complex recognizes and binds to the hypoxia responsive element (HRE) of hypoxia-inducible genes, thereby activating transcription.Synonyms: BHLHE17, Basic-helix-loop-helix-PAS protein MOP7, Class E basic helix-loop-helix protein 17, HIF-3 alpha, Hypoxia-inducible factor 3 alpha, IPAS, Inhibitory PAS domain protein, MOP7, Member of PAS protein 7, PASD7
    分子量
    approx. 65 kDa
    基因ID
    64344
    NCBI登录号
    NP_071907
    UniProt
    Q9Y2N7
    途径
    Warburg Effect
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