(1 reference)-
- 抗原 See all HIF3A 抗体
- HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
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抗原表位
- AA 581-592
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HIF3A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 产品特性
- Concentration Definition: by UV absorbance at 280 nm
- 过滤
- Sterile filtered
- 免疫原
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to aa 581-592 of mouse Hif3 a (Hypoxia Inducible Factor).
- 亚型
- IgG
- Top Product
- Discover our top product HIF3A Primary Antibody
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anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) antibody
HIF3A 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (AA 581-592) antibodyHIF3A 适用: 人, 小鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (AA 516-669) antibodyHIF3A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (AA 1-669) antibodyHIF3A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (AA 355-669) antibodyHIF3A 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4C2 unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (C-Term) antibodyHIF3A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (AA 1-363) antibodyHIF3A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (Internal Region) antibodyHIF3A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) (N-Term) antibodyVerified HIF3A 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- This affinity-purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 72 kDa in size corresponding to Hif3 a protein by western blotting in the appropriate cell lysate or extract. This antibody is expected to cross-react with mouse and rat Hif3 a due to sequence homology.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.2 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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: "Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2." in: Molecular and cellular biology, Vol. 26, Issue 22, pp. 8336-46, (2006) (PubMed).
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: "Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2." in: Molecular and cellular biology, Vol. 26, Issue 22, pp. 8336-46, (2006) (PubMed).
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- 抗原
- HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))
- 别名
- HIF3 alpha (HIF3A 产品)
- 别名
- HIF-3A antibody, IPAS antibody, MOP7 antibody, PASD7 antibody, bHLHe17 antibody, Ipas antibody, NEPAS antibody, Mop7 antibody, HIF3A antibody, hypoxia inducible factor 3 alpha subunit antibody, hypoxia inducible factor 3, alpha subunit antibody, HIF3A antibody, Hif3a antibody
- 背景
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One of the most important factors in the cellular response to hypoxia is hypoxia-inducible factor (HIF), which transcriptionally activates genes encoding proteins that mediate adaptive responses to reduced oxygen availability. HIF is a heterodimer consisting of one of three PRIVATE ''TYPE=PICT;ALT={alpha}''subunits (HIF1-aPRIVATE ''TYPE=PICT;ALT={alpha}'', HIF2-a,PRIVATE ''TYPE=PICT;ALT={alpha}'' or HIF3-a)PRIVATE ''TYPE=PICT;ALT={alpha}'' bound to the aryl hydrocarbon receptor nuclear translocator (ARNT) that is also known as HIF1-b. HIF-aPRIVATE ''TYPE=PICT;ALT={alpha}'' is a member of the basic helix-loop-helix (bHLH) superfamily, in which the HLH domain mediates subunit dimerization while the basic domain binds to DNA. HIF target genes play critical roles in metabolism, angiogenesis, cell proliferation, and cell survival; in fact, HIF3-a may be a marker for tumor growth and angiogenesis . Examples of HIF target genes include VEGF, glucose transporter 1 (GLUT1), and EPO. HIF binds to the hypoxia-responsive
Synonyms: HIF3 alpha antibody, HIF3A antibody, Hypoxia Inducible Factor 3 alpha antibody, Hypoxia inducible factor 3 alpha subunit antibody, Hypoxia inducible factor three alpha antibody, Inhibitory PAS domain protein antibody, IPAS antibody - 基因ID
- 53417, 170295859
- UniProt
- Q0VBL6
- 途径
- Warburg Effect
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