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SET/TAF-I 抗体

This 兔 多克隆 antibody specifically detects SET/TAF-I in WB 和 IHC (p). It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN498343
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for SET/TAF-I 抗体 (ABIN498343)

抗原

See all SET/TAF-I (SET) 抗体
SET/TAF-I (SET) (SET Nuclear Oncogene (SET))

适用

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  • 47
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  • 2
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  • 1
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  • 1
人, 大鼠

宿主

  • 77
  • 6
  • 2

克隆类型

  • 56
  • 28
多克隆

标记

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  • 6
  • 4
  • 3
  • 3
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  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This SET/TAF-I antibody is un-conjugated

应用范围

  • 61
  • 30
  • 27
  • 27
  • 19
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  • 7
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of TAF I p48 protein. (region surrounding Arg318)

    交叉反应 (详细)

    Species reactivity (expected):Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    纯度

    > 95 % by SDS-PAGE
  • 应用备注

    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    SET/TAF-I (SET) (SET Nuclear Oncogene (SET))

    别名

    SET / I2PP2A

    背景

    For gene transcription governed by RNA polymerase I, the human transcription factor SL1 (mouse TIF-IB) directs the assembly of initiation complexes at the prompter. Like TFIID, which directs transcription by RNA polymerase II, SL1/TIF-IB contains the TATA-binding protein (TBP) and a set of TBP-associated factors (TAFs). The three TAF I subunits, hTAF I p110, hTAF I p63 and hTAF p48 (or mouse TAF I p95, TAF I p68 and TAF I p48) are all integral components of SL1/TIF-IB. The mutually exclusive binding of either TAF I or TAF II subunits to TBP is believed to direct the formation of promoter and RNA polymerase-specific complexes.Synonyms: I-2PP2A, IGAAD, Inhibitor of granzyme A-activated DNase, PHAPII, Phosphatase 2A inhibitor I2PP2A, TAF-I, Template-activating factor I

    分子量

    approx. 53 kDa

    基因ID

    6418

    NCBI登录号

    NP_001116293

    UniProt

    H0UI37

    途径

    Apoptosis
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