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- 抗原 See all NR1I3 抗体
- NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR1I3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of MB67 protein. (region surrounding Thr102)
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- Affinity chromatography
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product NR1I3 Primary Antibody
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anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) antibody
NR1I3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 2-351) antibodyNR1I3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 180-229) antibodyNR1I3 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, Pig, 马, 兔, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (Internal Region) antibodyNR1I3 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) antibodyNR1I3 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 1-352) antibodyNR1I3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (C-Term) antibodyNR1I3 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (N-Term) antibodyNR1I3 适用: 人, 大鼠, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (AA 103-352) antibodyNR1I3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (N-Term) antibodyNR1I3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
- 别名
- NR1I3 (NR1I3 产品)
- 别名
- AA209988 antibody, AI551208 antibody, CAR antibody, CAR-beta antibody, Care2 antibody, ESTM32 antibody, MB67 antibody, CAR1 antibody, CXR antibody, nuclear receptor subfamily 1 group I member 3 antibody, nuclear receptor subfamily 1, group I, member 3 antibody, NR1I3 antibody, Nr1i3 antibody
- 背景
- This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: CAR, Constitutive activator of retinoid response, Constitutive active response, Constitutive androstane receptor, MB67, Nuclear receptor subfamily 1 group I member 3, Orphan nuclear receptor MB67
- 分子量
- approx. 35 kDa
- 基因ID
- 9970
- NCBI登录号
- NP_001070948
- UniProt
- Q14994
- 途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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