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Aryl Hydrocarbon Receptor 抗体

AHR 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498228
发货至: 中国
  • 抗原 See all Aryl Hydrocarbon Receptor (AHR) 抗体
    Aryl Hydrocarbon Receptor (AHR)
    适用
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    人, 小鼠, 大鼠
    宿主
    • 96
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    克隆类型
    • 95
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    多克隆
    标记
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    This Aryl Hydrocarbon Receptor antibody is un-conjugated
    应用范围
    • 72
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    This antibody detects endogenous levels of AhR protein.
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product AHR Primary Antibody
  • 应用备注
    Western Blot: 1/500approx. 1/1000. Immunofluorescence: 1/50approx. 1/200. Immunohistochemistry on Paraffin Sections: 1/50approx. 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Aryl Hydrocarbon Receptor (AHR)
    别名
    Ah Receptor (AhR) (AHR 产品)
    别名
    AHR antibody, ahr1 antibody, ahr antibody, bHLHe76 antibody, Ah antibody, Ahh antibody, Ahre antibody, In antibody, aryl hydrocarbon receptor S homeolog antibody, aryl hydrocarbon receptor antibody, aryl-hydrocarbon receptor antibody, ahr.S antibody, AHR antibody, ahr antibody, Ahr antibody
    背景
    The Aryl Hydrocarbon Receptor (AHR), also known as the dioxin receptor, is a ligand-activated helix/loop/helix transcription factor found in a variety of vertebrate species. The known ligands for AHR are foreign planar aromatic compounds, such as polycyclic aromatic compounds and halogenated aromatic compounds such as 2,3,7,8-TetraChloroDibenzo-p-Dioxin (TCDD). Unlike the steroid/thyroid hormone receptors, there is no known physiological ligand for the AH Receptor. Studies indicate that in non-ligand activated cells, AHR is found complexed with HSP90 predominantly in the cytoplasm. Upon binding to an agonist, the ligand-activated AHR is believed to transform to a nuclear, DNA binding form. This transformation process appears to involve dissociation of HSP90 from AHR followed by formation of a heterodimer with AHR nuclear translocator protein (Arnt). The AHR-ligand complex appears to initiate gene transcription of cytochrome P450 1A1.Synonyms: AHR, Aryl hydrocarbon receptor, BHLHE76
    分子量
    approx. 96 kDa
    基因ID
    196
    NCBI登录号
    NP_001612
    UniProt
    P35869
    途径
    Regulation of Cell Size
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