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Aryl Hydrocarbon Receptor 抗体 (C-Term)

AHR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043054
发货至: 中国
  • 抗原 See all Aryl Hydrocarbon Receptor (AHR) 抗体
    Aryl Hydrocarbon Receptor (AHR)
    抗原表位
    • 15
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    AA 832-848, C-Term
    适用
    • 105
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    宿主
    • 99
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    克隆类型
    • 98
    • 19
    多克隆
    标记
    • 68
    • 6
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    This Aryl Hydrocarbon Receptor antibody is un-conjugated
    应用范围
    • 74
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    • 10
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    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Aryl hydrocarbon receptor(AHR) detection. Tested with WB in Human.
    序列
    HPSEARPFPD LTSSGFL
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Aryl hydrocarbon receptor(AHR) detection. Tested with WB in Human.
    Gene Name: aryl hydrocarbon receptor
    Protein Name: Aryl hydrocarbon receptor
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human AHR (832-848aa HPSEARPFPDLTSSGFL).
    亚型
    IgG
    Top Product
    Discover our top product AHR Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    Aryl Hydrocarbon Receptor (AHR)
    别名
    AHR (AHR 产品)
    别名
    AHR antibody, ahr1 antibody, ahr antibody, bHLHe76 antibody, Ah antibody, Ahh antibody, Ahre antibody, In antibody, aryl hydrocarbon receptor S homeolog antibody, aryl hydrocarbon receptor antibody, aryl-hydrocarbon receptor antibody, ahr.S antibody, AHR antibody, ahr antibody, Ahr antibody
    背景
    AHR(aryl hydrocarbon receptor), also called bHLHe76, is a member of the family of basic helix-loop-helix transcription factors. AhR is a cytosolic transcription factor that is normally inactive, bound to several co-chaperones. The AHR gene is mapped on 7p21.1. Estrogenic actions of AHR agonists were detected in wildtype ovariectomized mouse uteri, but were absent in Ahr -/- or Er-alpha -/- ovariectomized mice. Complex assembly and ubiquitin ligase activity of CUL4B(AHR) in vitro and in vivo are dependent on the AHR ligand. In the CUL4B(AHR) complex, ligand-activated AHR acts as a substrate-specific adaptor component that targets sex steroid receptors for degradation. Cd4-positive cells from mice lacking Ahr developed Th17 responses but failed to produce Il22 and did not show enhanced Th17 development. Activation of Ahr during induction of EAE accelerated disease onset and increased pathology in wildtype mice, but not in Ahr -/- mice. The TDO-AHR pathway is active in human brain tumors and is associated with malignant progression and poor survival. Ahr activity within ROR-gamma-t-positive ILC could be induced by dietary ligands such as those contained in vegetables of the family Brassicaceae.

    Synonyms: Ah receptor antibody|AHR antibody|AHR_HUMAN antibody|Aromatic hydrocarbon receptor antibody|Aryl hydrocarbon receptor antibody|Aryl hydrocarbon receptor precursor antibody|bHLHe76 antibody|Class E basic helix loop helix protein 76 antibody|Class E basic helix-loop-helix protein 76 antibody|HGNC:348 antibody
    UniProt
    P35869
    途径
    Regulation of Cell Size
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