-
- 抗原 See all GRB10 抗体
- GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This GRB10 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of GRB10 protein. (region surrounding Leu63)
- 交叉反应 （详细）
- Species reactivity (tested):Human.
- 纯化方法
- Affinity chromatography using epitope-specific immunogen
- 纯度
- > 95 % (by SDS-PAGE)
- Top Product
- Discover our top product GRB10 Primary Antibody
-
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (AA 392-594) antibody
GRB10 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (AA 61-150) antibodyGRB10 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (Ser428) antibodyGRB10 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (AA 1-100) antibodyGRB10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (N-Term) antibodyGRB10 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (AA 33-82) antibodyGRB10 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (AA 1-536) antibodyGRB10 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (AA 61-150) antibodyGRB10 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (pTyr67) antibodyGRB10 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 10 (GRB10) (AA 1-536) antibodyGRB10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
- 抗原
- GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))
- 别名
- GRB10 / GRBIR (GRB10 产品)
- 别名
- grb10 antibody, zgc:91987 antibody, GRB10 antibody, grb-10 antibody, grb-ir antibody, irbp antibody, meg1 antibody, rss antibody, LOC100224775 antibody, 5730571D09Rik antibody, AI325020 antibody, Meg1 antibody, mKIAA0207 antibody, RGD1566234 antibody, GRB-IR antibody, Grb-10 antibody, IRBP antibody, MEG1 antibody, RSS antibody, growth factor receptor bound protein 10 antibody, growth factor receptor-bound protein 10a antibody, growth factor receptor bound protein 10 L homeolog antibody, growth factor receptor-bound protein 10 antibody, GRB10 antibody, grb10a antibody, grb10 antibody, grb10.L antibody, LOC100434903 antibody, Grb10 antibody
- 背景
- Many growth factors function by binding receptors with intrinsic tyrosine kinase activity. Signaling by such receptors involves a series of intermediates characterized by SH2 domains that bind tyrosine phosphorylated receptors by a direct interaction between the SH2 domain and specific phosphotyrosine- containing receptor sequences. GRB7, a SH2 domain protein, has a single SH2 domain at its C-terminal, a central region with similarity to Ras GAP, and a proline-rich N terminus. A related SH2 domain-containing protein, GRB10, exhibits a high degree of homology with GRB7. GRB10 undergoes serine but not tyrosine phosphorylation in response to EGF treatment, but appears to bind to the EGF receptor poorly. GRB10 maps to mouse chromosome 11, in close proximity to the EGF receptor. Similarly, GRB7 maps to the same mouse chromosome near the EGF receptor-related protein HER2.Synonyms: Grb-IR, Growth factor receptor-bound protein 10, Insulin receptor-binding protein Grb-IR, KIAA0207
- 分子量
- approx. 67 kDa
- 基因ID
- 2887
- NCBI登录号
- NP_001001549
- UniProt
- Q13322
- 途径
- Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2
-
You are here:
