GRB10 抗体 (AA 33-82)
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北京 101111
Quick Overview for GRB10 抗体 (AA 33-82) (ABIN1532670)
抗原
See all GRB10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 33-82
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原理
- GRB10 Antibody
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特异性
- GRB10 Polyclonal Antibody detects endogenous levels of GRB10 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human GRB10. AA range:33-82
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))
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别名
- GRB10
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背景
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Synonyms: GRB10, GRBIR, KIAA0207, Growth factor receptor-bound protein 10, GRB10 adapter protein, Insulin receptor-binding protein Grb-IR
Background: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules.This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010],
Gene Name: GRB10
Protein Name: Growth factor receptor-bound protein 10
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分子量
- 67 kDa
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基因ID
- 2887
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OMIM
- 601523
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UniProt
- Q13322
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途径
- Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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