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GRB10 抗体 (AA 33-82)

This 兔 多克隆 antibody specifically detects GRB10 in WB, ELISA, IHC 和 IF. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN1532670
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for GRB10 抗体 (AA 33-82) (ABIN1532670)

抗原

See all GRB10 抗体
GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

适用

  • 77
  • 48
  • 36
  • 25
  • 1
人, 大鼠, 小鼠

宿主

  • 72
  • 17
  • 1
兔

克隆类型

  • 75
  • 15
多克隆

标记

  • 47
  • 6
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GRB10 antibody is un-conjugated

应用范围

  • 70
  • 47
  • 44
  • 34
  • 17
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 26
    • 13
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 33-82

    原理

    GRB10 Antibody

    特异性

    GRB10 Polyclonal Antibody detects endogenous levels of GRB10 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human GRB10. AA range:33-82

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))

    别名

    GRB10

    背景

    Synonyms: GRB10, GRBIR, KIAA0207, Growth factor receptor-bound protein 10, GRB10 adapter protein, Insulin receptor-binding protein Grb-IR

    Background: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules.This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010],

    Gene Name: GRB10

    Protein Name: Growth factor receptor-bound protein 10

    分子量

    67 kDa

    基因ID

    2887

    OMIM

    601523

    UniProt

    Q13322

    途径

    Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2
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