SGK1 抗体 (AA 323-352)
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Quick Overview for SGK1 抗体 (AA 323-352) (ABIN3032549)
抗原
See all SGK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 323-352
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交叉反应 (详细)
- Expected species reactivity: Rat, Primate
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 323-352 from the mouse protein was used as the immunogen for this Sgk1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Sgk1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Sgk1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))
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别名
- Sgk1
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背景
- This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. This enzyme is activated by protein phosphorylation and degraded via the ubiquitination and proteasome pathway. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene was identified on chromosome 12.
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UniProt
- Q9WVC6
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途径
- MAPK Pathway, Notch Signaling, Steroid Hormone Mediated Signaling Pathway
抗原
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