BRAF 抗体 (pThr598)
Our Local Distributor
北京 101111
Quick Overview for BRAF 抗体 (pThr598) (ABIN3032636)
抗原
See all BRAF 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pThr598
-
交叉反应 (详细)
- Expected species reactivity: Mouse, Rat, Bovine, Chicken
-
纯化方法
- Antigen affinity purified
-
免疫原
- This phospho-B-RAF antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT598 of human BRAF.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the phospho-B-RAF antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the phospho-B-RAF antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
-
别名
- BRAF
-
背景
- BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neuron. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.
-
UniProt
- P15056
-
途径
- MAPK Pathway, RTK signaling, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy
抗原
-