ATF2 抗体 (pSer322)
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北京 101111
Quick Overview for ATF2 抗体 (pSer322) (ABIN3029846)
抗原
See all ATF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer322
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纯化方法
- Antigen affinity purified
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免疫原
- This phospho-ATF2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS322 of human ATF2.
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亚型
- Ig Fraction
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应用备注
- Titration of the phospho-ATF2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the phospho-ATF2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- ATF2 (Activating Transcription Factor 2 (ATF2))
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别名
- ATF2
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背景
- ATF2 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.
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UniProt
- P15336
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途径
- MAPK Pathway, RTK signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
抗原
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