Parkin 抗体 (AA 387-417)
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- 抗原 See all Parkin (PARK2) 抗体
- Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
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抗原表位
- AA 387-417
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Parkin antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- 纯化方法
- Purified
- 免疫原
- A portion of amino acids 387-417 from the human protein was used as the immunogen for this Parkin antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PARK2 Primary Antibody
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anti-Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (AA 288-387) antibody
PARK2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (AA 1-300) antibodyPARK2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (AA 387-417), (C-Term) antibodyPARK2 适用: 人, 小鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB07373 unconjugated
anti-Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (AA 111-140) antibodyPARK2 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (AA 361-465) antibodyPARK2 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (AA 1-465) antibodyPARK2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (AA 1-144) antibodyPARK2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 6F5D2 unconjugated
anti-Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (AA 23-416) antibodyPARK2 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (AA 300-350) antibodyPARK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) (C-Term) antibodyPARK2 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Titration of the Parkin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:50-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the Parkin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
- 别名
- Parkin (PARK2 产品)
- 别名
- CG10523 antibody, Dmel\\CG10523 antibody, Dpark antibody, SD01679 antibody, dpk antibody, AR-JP antibody, LPRS2 antibody, PDJ antibody, PRKN antibody, Park antibody, Prkn antibody, si:ch211-123f21.1 antibody, zgc:112390 antibody, pdr-1 antibody, PARK2 antibody, parkin antibody, parkin RBR E3 ubiquitin protein ligase antibody, Parkinson disease (autosomal recessive, juvenile) 2, parkin antibody, park antibody, PRKN antibody, Prkn antibody, prkn antibody, CpipJ_CPIJ014867 antibody, Park2 antibody
- 背景
- Parkin possibly plays a role in the regulation of neuron death. Limits the production of reactive oxygen species (ROS). Regulates cyclin-E during neuronal apoptosis. In collaboration with CHPF isoform 2, may enhance cell viability and protect cells from oxidative stress. Independently of its ubiquitin ligase activity, protects from apoptosis by the transcriptional repression of p53/TP53. May protect neurons against alpha synuclein toxicity, proteasomal dysfunction, GPR37 accumulation, and kainate-induced excitotoxicity. May play a role in controlling neurotransmitter trafficking at the presynaptic terminal and in calcium-dependent exocytosis. May represent a tumor suppressor gene. [UniProt]
- UniProt
- O60260
- 途径
- Autophagy, Ubiquitin Proteasome Pathway
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