Neuregulin 2 抗体 (AA 830-855)
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Quick Overview for Neuregulin 2 抗体 (AA 830-855) (ABIN3031976)
抗原
See all Neuregulin 2 (NRG2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 830-855
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交叉反应 (详细)
- Expected species reactivity: Rat
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纯化方法
- Purified
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免疫原
- A portion of amino acids 830~855 from the human protein was used as the immunogen for this NRG2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the NRG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the NRG2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Neuregulin 2 (NRG2)
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别名
- NRG2
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背景
- Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. There are six NRG2 alternatively spliced transcripts which are variable between the epidermal growth factor-like (EGF-like) and the transmembrane domains. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease.
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UniProt
- O14511
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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