Neuregulin 2 抗体 (C-Term)
(5 references)-
- 抗原 See all Neuregulin 2 (NRG2) 抗体
- Neuregulin 2 (NRG2)
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抗原表位
- AA 358-389, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Neuregulin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- Rat
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This NRG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-389 amino acids from the C-terminal region of human NRG2.
- 克隆位点
- RB1278
- 亚型
- Ig Fraction
- Top Product
- Discover our top product NRG2 Primary Antibody
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anti-Neuregulin 2 (NRG2) antibody
NRG2 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (AA 116-215) antibodyNRG2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D2 unconjugated
anti-Neuregulin 2 (NRG2) (AA 112-405) antibodyNRG2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) antibodyNRG2 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (Internal Region) antibodyNRG2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (AA 116-215) antibodyNRG2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (AA 101-211) antibodyNRG2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (AA 618-836) antibodyNRG2 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (AA 830-855) antibodyNRG2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Neuregulin 2 (NRG2) (AA 297-311), (Extracellular), (N-Term) antibodyNRG2 适用: 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "Characterization of the human NTAK gene structure and distribution of the isoforms for rat NTAK mRNA." in: Gene, Vol. 255, Issue 1, pp. 15-24, (2000) (PubMed).
: "The human neuregulin-2 (NRG2) gene: cloning, mapping and evaluation as a candidate for the autosomal recessive form of Charcot-Marie-Tooth disease linked to 5q." in: Human genetics, Vol. 104, Issue 4, pp. 326-32, (1999) (PubMed).
: "A novel brain-derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4." in: Journal of biochemistry, Vol. 122, Issue 3, pp. 675-80, (1998) (PubMed).
: "Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases." in: Nature, Vol. 387, Issue 6632, pp. 512-6, (1997) (PubMed).
: "Characterization of a neuregulin-related gene, Don-1, that is highly expressed in restricted regions of the cerebellum and hippocampus." in: Molecular and cellular biology, Vol. 17, Issue 7, pp. 4007-14, (1997) (PubMed).
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: "Characterization of the human NTAK gene structure and distribution of the isoforms for rat NTAK mRNA." in: Gene, Vol. 255, Issue 1, pp. 15-24, (2000) (PubMed).
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- 抗原
- Neuregulin 2 (NRG2)
- 别名
- NRG2 (NRG2 产品)
- 别名
- NRG2 antibody, Don1 antibody, NTAK antibody, DON1 antibody, HRG2 antibody, NTAK_alpha2a antibody, Ntak antibody, neuregulin 2 antibody, NRG2 antibody, Nrg2 antibody
- 背景
- Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. There are six NRG2 alternatively spliced transcripts which are variable between the epidermal growth factor-like (EGF-like) and the transmembrane domains. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease.
- 分子量
- 91679
- NCBI登录号
- NP_001171864, NP_004874, NP_053584, NP_053585, NP_053586
- UniProt
- O14511
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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