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- 抗原 See all HLA-B 抗体
- HLA-B (Major Histocompatibility Complex, Class I, B (HLA-B))
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抗原表位
- AA 62-90
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HLA-B antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Purified
- 免疫原
- A portion of amino acids 62-90 from the human protein was used as the immunogen for this HLA-B antibody.
- 克隆位点
- 528CT10-4-1
- 亚型
- IgM
- Top Product
- Discover our top product HLA-B Primary Antibody
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anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 26-309) antibody
HLA-B 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 241-362) antibodyHLA-B 适用: 人 WB, ELISA, FACS, IHC, ICC 宿主: 小鼠 Monoclonal 2A11G7 unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 75-107), (N-Term) antibodyHLA-B 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB47637 unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 1-100) antibodyHLA-B 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) antibodyHLA-B 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 25-308) antibodyHLA-B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 1-362) antibodyHLA-B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 209-295) antibodyHLA-B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D4B6 unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 243-308) antibodyHLA-B 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 197-306) antibodyHLA-B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Titration of the HLA-B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:250
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the HLA-B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- HLA-B (Major Histocompatibility Complex, Class I, B (HLA-B))
- 别名
- HLA-B (HLA-B 产品)
- 别名
- AS antibody, HLAB antibody, SPDA1 antibody, mhc1b antibody, major histocompatibility complex, class I, B antibody, major histocompatibility complex nonclassical class Ib L homeolog antibody, HLA-B antibody, BOLA-B antibody, MAMU-B18 antibody, DKFZP469N1225 antibody, mhc1b.L antibody
- 背景
- HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
- UniProt
- P03989
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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