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FGFR1 抗体 (AA 441-470)

This anti-FGFR1 antibody is a 兔 多克隆 antibody detecting FGFR1 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN3029718
发货至: 中国

Quick Overview for FGFR1 抗体 (AA 441-470) (ABIN3029718)

抗原

See all FGFR1 抗体
FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This FGFR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    AA 441-470

    交叉反应 (详细)

    Expected species reactivity: Chicken, Mouse, Rat

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 441-470 from the human protein was used as the immunogen for this FGFR antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the FGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the FGFR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

    背景

    FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene can lead to Pfeiffer syndrome and Jackson-Weiss syndrome.

    UniProt

    P11362

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins
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