BAD 抗体 (AA 53-81)
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Quick Overview for BAD 抗体 (AA 53-81) (ABIN3030115)
抗原
See all BAD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 53-81
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 53-81 from the human protein was used as the immunogen for this Bad antibody.
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应用备注
- Titration of the Bad antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Bad antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- BAD (BCL2-Associated Agonist of Cell Death (BAD))
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别名
- Bad
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背景
- Bad is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein.
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UniProt
- Q92934
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途径
- MAPK Pathway, PI3K-Akt Signaling, RTK signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
抗原
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