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ATG5 抗体 (AA 209-238)

This anti-ATG5 antibody is a 兔 多克隆 antibody detecting ATG5 in WB, IHC, ELISA 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN3030035
发货至: 中国

Quick Overview for ATG5 抗体 (AA 209-238) (ABIN3030035)

抗原

See all ATG5 抗体
ATG5 (ATG5 Autophagy Related 5 (ATG5))

适用

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人, 小鼠

宿主

  • 80
  • 63
  • 4
  • 1

克隆类型

  • 78
  • 70
多克隆

标记

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This ATG5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 45
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    AA 209-238

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 209-238 from the human protein was used as the immunogen for this anti-ATG5 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the anti-ATG5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:25,Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the anti-ATG5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    ATG5 (ATG5 Autophagy Related 5 (ATG5))

    别名

    ATG5

    背景

    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. APG5, required for autophagy, conjugates to ATG12 and associates with an isolation membrane to form a cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. APG5 may also play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.

    UniProt

    Q9H1Y0

    途径

    Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
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