ATG5 抗体 (AA 209-238)
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Quick Overview for ATG5 抗体 (AA 209-238) (ABIN3030035)
抗原
See all ATG5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 209-238
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 209-238 from the human protein was used as the immunogen for this anti-ATG5 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the anti-ATG5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:25,Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the anti-ATG5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- ATG5 (ATG5 Autophagy Related 5 (ATG5))
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别名
- ATG5
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背景
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. APG5, required for autophagy, conjugates to ATG12 and associates with an isolation membrane to form a cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. APG5 may also play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
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UniProt
- Q9H1Y0
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途径
- Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
抗原
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