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GIP 抗体

GIP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4951171
发货至: 中国
  • 抗原 See all GIP 抗体
    GIP (Gastric Inhibitory Polypeptide (GIP))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This GIP antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    Amino acids Y52-Q93 from the human protein were used as the immunogen for the GIP antibody.
    亚型
    IgG
    Top Product
    Discover our top product GIP Primary Antibody
  • 应用备注
    Optimal dilution of the GIP antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (FFPE): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the GIP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    GIP (Gastric Inhibitory Polypeptide (GIP))
    别名
    GIP / Gastric inhibitory polypeptide (GIP 产品)
    别名
    GIP antibody, xgip antibody, Gludins antibody, RATGLUDINS antibody, gastric inhibitory polypeptide antibody, gastric inhibitory polypeptide L homeolog antibody, GIP antibody, gip antibody, Gip antibody, gip.L antibody
    背景
    Gastric inhibitory polypeptide (GIP), also known as the glucose-dependent insulinotropic peptide, is an inhibiting hormone of the secretin family of hormones. GIP is thought to have significant effects on fatty acid metabolism through stimulation of lipoprotein lipase activity in adipocytes. Additionally, GIP release has been demonstrated in the ruminant animal and may play a role in nutrient partitioning in milk production (lipid metabolism). Recently, GIP appeared as a major player in bone remodelling. It was evidenced that genetic ablation of the GIP receptor in mice resulted in profound alterations of bone microarchitecture through modification of the adipokine network. Furthermore, the deficiency in GIP receptors has also been associated in mice with a dramatic decrease in bone quality and a subsequent increase in fracture risk.
    UniProt
    P09681
    途径
    Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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