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Crossover junction endonuclease EME1 (EME1) 抗体

EME1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4950913
发货至: 中国
  • 抗原 See all Crossover junction endonuclease EME1 (EME1) 抗体
    Crossover junction endonuclease EME1 (EME1)
    适用
    • 20
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    人, 大鼠
    宿主
    • 17
    • 4
    克隆类型
    • 19
    • 2
    多克隆
    标记
    • 17
    • 2
    • 1
    • 1
    非结合性
    应用范围
    • 16
    • 8
    • 4
    • 2
    • 1
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    Amino acids DKERQNLLADIQVRRGEGVTSTSRRIGPELSRRIYLQMTTLQ of human EME1 were used as the immunogen for the EME1 antibody.
    亚型
    IgG
    Top Product
    Discover our top product EME1 Primary Antibody
  • 应用备注
    Optimal dilution of the EME1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the EME1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    Crossover junction endonuclease EME1 (EME1)
    别名
    EME1 (EME1 产品)
    别名
    6820428D13 antibody, essential meiotic structure-specific endonuclease 1 antibody, Eme1 antibody
    背景
    Crossover junction endonuclease EME1 is an enzyme that in humans is encoded by the EME1 gene. It is mapped to 17q21.33. This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. Also, this protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.
    UniProt
    Q96AY2
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