Crossover junction endonuclease EME1 产品
(Crossover junction endonuclease EME1 (EME1))
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Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'- flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks. {ECO:0000269|PubMed:14609959}.
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Featured Crossover junction endonuclease EME1 Categories
Crossover junction endonuclease EME1 抗体
High quality antibodies with extensive validation data.
Crossover junction endonuclease EME1 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Crossover junction endonuclease EME1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (5)
Cat. No.
ABIN530922
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7148691
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, ICC
Validations
- (2)
Cat. No.
ABIN6256869
Quantity
100 μL
Datasheet
Datasheet
Recommended Crossover junction endonuclease EME1 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6201005
Quantity
96 tests
Datasheet
Datasheet
Recommended Crossover junction endonuclease EME1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1352746
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3079307
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3124939
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Crossover junction endonuclease EME1 Products
: "The EGFR-STAT3 oncogenic pathway up-regulates the Eme1 endonuclease to reduce DNA damage after topoisomerase I inhibition." in: Cancer research, Vol. 68, Issue 3, pp. 815-25, (2008) (PubMed).: "Cleavage mechanism of human Mus81-Eme1 acting on Holliday-junction structures." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 10, pp. 3757-62, (2008) (PubMed).
: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, (2006) (PubMed).
Synonyms and alternative names related to Crossover junction endonuclease EME1
essential meiotic structure-specific endonuclease 1 (Eme1), 6820428D13Protein level used designations for Crossover junction endonuclease EME1
- crossover junction endonuclease EME1
- essential meiotic endonuclease 1 homolog 1
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