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CROCC 抗体

(Ciliary Rootlet Coiled-Coil, Rootletin (CROCC))
Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Contributes to centrosome cohesion before mitosis.

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Featured CROCC Categories

CROCC 抗体

High quality antibodies with extensive validation data.

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Latest Publications for our CROCC Products

Mahen: "Stable centrosomal roots disentangle to allow interphase centriole independence." in: PLoS biology, Vol. 16, Issue 4, pp. e2003998, (2019) (PubMed).

Flanagan, Stavenschi, Basavaraju, Gaboriau, Hoey, Morrison: "Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification." in: Molecular biology of the cell, Vol. 28, Issue 6, pp. 736-745, (2017) (PubMed).

Wallmeier, Al-Mutairi, Chen, Loges, Pennekamp, Menchen, Ma, Shamseldin, Olbrich, Dougherty, Werner, Alsabah, Köhler, Jaspers, Boon, Griese, Schmitt-Grohé, Zimmermann, Koerner-Rettberg, Horak, Kintner et al.: "Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia. ..." in: Nature genetics, Vol. 46, Issue 6, pp. 646-51, (2014) (PubMed).

Löffler, Fechter, Liu, Poppelreuther, Krämer: "DNA damage-induced centrosome amplification occurs via excessive formation of centriolar satellites." in: Oncogene, Vol. 32, Issue 24, pp. 2963-72, (2013) (PubMed).

Rohena, Peng, Johnson, Crews, Mooberry: "Chemically diverse microtubule stabilizing agents initiate distinct mitotic defects and dysregulated expression of key mitotic kinases." in: Biochemical pharmacology, Vol. 85, Issue 8, pp. 1104-14, (2013) (PubMed).

Synonyms and alternative names related to CROCC

ciliary rootlet coiled-coil, rootletin (CROCC), ciliary rootlet coiled-coil, rootletin (Crocc), rootletin (AOR_1_1088164), rootletin (CpipJ_CPIJ001714), ROLT

Protein level used designations for CROCC

  • Tax1-binding protein 2
  • ciliary rootlet coiled-coil protein
  • rootletin
  • rootletin, ciliary rootlet protein
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