FAT Atypical Cadherin 2 (FAT2) 抗体
FAT2
适用: 人
IF, FACS, IHC (p)
宿主: 小鼠
Monoclonal
8C5
unconjugated
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- 抗原 See all FAT Atypical Cadherin 2 (FAT2) 抗体
- FAT Atypical Cadherin 2 (FAT2)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Protein G affinity chromatography
- 免疫原
- A recombinant human Protocadherin Fat 2 fusion protein was used as the immunogen for this FAT2 antibody.
- 克隆位点
- 8C5
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product FAT2 Primary Antibody
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anti-FAT Atypical Cadherin 2 (FAT2) (AA 123-314) antibody
FAT2 适用: 人 IF, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FAT Atypical Cadherin 2 (FAT2) antibodyFAT2 适用: 人 IF, FACS, IHC, StM 宿主: 小鼠 Monoclonal 8C5 unconjugated
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- 应用备注
- Titering of the FAT2 antibody may be required for optimal performance.\. FACS: 0.5-1 μg/million cells in 0.1ml, Immunofluorescence: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
- 储存液
- Azide free
- 储存条件
- 4 °C,-20 °C
- 储存方法
- The FAT2 antibody (with azide) can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- 抗原
- FAT Atypical Cadherin 2 (FAT2)
- 别名
- FAT2 / Protocadherin Fat 2 (FAT2 产品)
- 别名
- EMI2 antibody, Fath2 antibody, Gm523 antibody, mKIAA0811 antibody, CDHF8 antibody, CDHR9 antibody, HFAT2 antibody, MEGF1 antibody, FAT atypical cadherin 2 antibody, Fat2 antibody, FAT2 antibody
- 背景
- Recognizes a protein of 480 kDa, which is identified as FAT2. The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell-to-cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT2 (FAT tumor suppressor homolog 2) is a single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins. FAT2 contains one Laminin G-like domain, two EGF-like domains and 32 cadherin domains and is believed to function as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development.
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