FAT Atypical Cadherin 2 (FAT2) 抗体
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- 抗原 See all FAT Atypical Cadherin 2 (FAT2) 抗体
- FAT Atypical Cadherin 2 (FAT2)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Recognizes a protein of 480 kDa, which is identified as FAT2. The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell-to-cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including -catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT2 (FAT tumor suppressor homolog 2) is a single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins. FAT2 contains one Laminin G-like domain, two EGF-like domains and 32 cadherin domains and is believed to function as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Purified recombinant human FAT2 fusion protein.
- 克隆位点
- 8C5
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product FAT2 Primary Antibody
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anti-FAT Atypical Cadherin 2 (FAT2) (AA 123-314) antibody
FAT2 适用: 人 IF, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FAT Atypical Cadherin 2 (FAT2) antibodyFAT2 适用: 人 IF, FACS, IHC, StM 宿主: 小鼠 Monoclonal 8C5 unconjugated
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Esophagus, Cervix, Uterus, Tonsil or Cerebellum.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- FAT Atypical Cadherin 2 (FAT2)
- 别名
- FAT2 (FAT2 产品)
- 别名
- EMI2 antibody, Fath2 antibody, Gm523 antibody, mKIAA0811 antibody, CDHF8 antibody, CDHR9 antibody, HFAT2 antibody, MEGF1 antibody, FAT atypical cadherin 2 antibody, Fat2 antibody, FAT2 antibody
- 背景
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FAT tumor suppressor homolog 2 (HFAT2), cadherin family member 8 (CDHF8), cadherin-related family member 9 (CDHR9), multiple EGF-like domains protein 1, multiple epidermal growth factor-like domains 1 (MEGF1), multiple epidermal growth factor-like domains protein 1, protocadherin FAT2.,Protocadherin FAT2 (FAT Atypical Cadherin 2)
Cellular localisation: Cell Surface - 分子量
- 480kDa
- 基因ID
- 2196, 591255
- UniProt
- Q9NYQ8
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