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DC-SIGN/CD209 抗体

CD209 适用: 人 FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal C209-1781 unconjugated
产品编号 ABIN4949596
发货至: 中国
  • 抗原 See all DC-SIGN/CD209 (CD209) 抗体
    DC-SIGN/CD209 (CD209) (CD209)
    适用
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    宿主
    • 76
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    小鼠
    克隆类型
    • 75
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    单克隆
    标记
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    This DC-SIGN/CD209 antibody is un-conjugated
    应用范围
    • 73
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    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Protein G affinity chromatography
    免疫原
    A human partial recombinant protein was used as the immunogen for the DC-SIGN antibody.
    克隆位点
    C209-1781
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CD209 Primary Antibody
  • 应用备注
    Titering of the DC-SIGN antibody may be required for optimal performance.\. IF: 1-2 μg/mL,Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the DC-SIGN antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    DC-SIGN/CD209 (CD209) (CD209)
    别名
    DC-SIGN / CD209 (CD209 产品)
    别名
    CDSIGN antibody, CLEC4L antibody, DC-SIGN antibody, DC-SIGN1 antibody, cd209 antibody, CLEC4M antibody, si:ch211-224h1.3 antibody, CD209 antibody, CIRE antibody, Dcsign antibody, SIGN-R1 antibody, SIGNR5 antibody, Cd209 antibody, CD209 molecule antibody, CD209a antigen antibody, CD209 antigen-like protein D antibody, CD209c molecule antibody, CD209 antigen antibody, CD209 antibody, cd209 antibody, Cd209a antibody, LOC100529184 antibody, Cd209c antibody, LOC100460708 antibody, LOC105484282 antibody
    背景
    DC-SIGN / CD209 is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.
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