c-Rel 抗体
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北京 101111
Quick Overview for c-Rel 抗体 (ABIN4906804)
抗原
See all c-Rel 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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免疫原
- This REL monoclonal antibody is generated from mouse immunized with REL recombinant protein.
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亚型
- IgG2b
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anti-REL proto-oncogene (c-Rel) (pSer503) antibody
c-Rel 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) antibodyc-Rel 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) antibodyc-Rel 适用: 人, 小鼠 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 1E7 unconjugated
anti-REL proto-oncogene (c-Rel) (AA 1-300) antibodyc-Rel 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) (AA 268-306), (Middle Region) antibodyc-Rel 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) (Internal Region) antibodyVerified c-Rel 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) (C-Term) antibodyc-Rel 适用: 人, 犬, 马, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) (Thr69) antibodyc-Rel 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-REL proto-oncogene (c-Rel) (AA 1-209) antibodyc-Rel 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IF() -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- c-Rel (REL proto-oncogene (c-Rel))
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别名
- C-rel
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背景
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Synonyms: C-Rel, Proto-oncogene c-Rel, REL
Background: Proto-oncogene that may play a role in differentiation and lymphopoiesis. NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. The NF-kappa-B heterodimer RELA/p65-c-Rel is a transcriptional activator.
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基因ID
- 5966
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UniProt
- Q04864
抗原
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