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- 抗原 See all Nischarin (NISCH) 抗体
- Nischarin (NISCH)
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Nischarin antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- This gene encodes a nonadrenergic imidazoline-1 receptor protein that localizes to the cytosol and anchors to the inner layer of the plasma membrane. The orthologous mouse protein has been shown to influence cytoskeletal organization and cell migration by binding to alpha-5-beta-1 integrin. In humans, this protein has been shown to bind to the adapter insulin receptor substrate 4 (IRS4) to mediate translocation of alpha-5 integrin from the cell membrane to endosomes. Expression of this protein was reduced in human breast cancers while its overexpression reduced tumor growth and metastasis, possibly by limiting the expression of alpha-5 integrin. In human cardiac tissue, this gene was found to affect cell growth and death while in neural tissue it affected neuronal growth and differentiation. Alternative splicing results in multiple transcript variants encoding differerent isoforms. Some isoforms lack the expected C-terminal domains of a functional imidazoline receptor. [provided by RefSeq, Jan 2013]
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human NISCH.
- 亚型
- IgG
- Top Product
- Discover our top product NISCH Primary Antibody
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anti-Nischarin (NISCH) (AA 500-700) antibody
NISCH 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nischarin (NISCH) (AA 1246-1345) antibodyNISCH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B8 unconjugated
anti-Nischarin (NISCH) (AA 1246-1346) antibodyNISCH 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nischarin (NISCH) (AA 1335-1435) antibodyNISCH 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nischarin (NISCH) (AA 5-38) antibodyNISCH 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB55910 unconjugated
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- 应用备注
- WB 1:200-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C.
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- 抗原
- Nischarin (NISCH)
- 别名
- NISCH (NISCH 产品)
- 别名
- NISCH antibody, IRAS antibody, 1200007D05Rik antibody, 3202002H23Rik antibody, AW494485 antibody, I-1 antibody, IR1 antibody, hIRAS antibody, nischarin antibody, nischarin S homeolog antibody, NISCH antibody, Cyan7822_6841 antibody, nisch.S antibody, nisch antibody, Nisch antibody
- 基因ID
- 11188
- UniProt
- Q9Y2I1
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