Nischarin 抗体 (AA 1100-1150)
-
- 抗原 See all Nischarin (NISCH) 抗体
- Nischarin (NISCH)
-
抗原表位
- AA 1100-1150
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Nischarin antibody is un-conjugated
-
应用范围
- Immunoprecipitation (IP)
- 原理
- Rabbit anti-NISCH Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 1100 and 1150
- 亚型
- IgG
- Top Product
- Discover our top product NISCH Primary Antibody
-
anti-Nischarin (NISCH) (AA 500-700) antibody
NISCH 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nischarin (NISCH) (AA 1246-1345) antibodyNISCH 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B8 unconjugated
anti-Nischarin (NISCH) (AA 1246-1346) antibodyNISCH 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nischarin (NISCH) (AA 1335-1435) antibodyNISCH 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nischarin (NISCH) (AA 5-38) antibodyNISCH 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB55910 unconjugated
-
- 应用备注
-
IP: 2 - 10 μg/mg lysate
WB: Not recommended. ABIN7451170 has not performed satisfactorily when used for WB of NISCH in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of NISCH.
- 限制
- 仅限研究用
-
- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
-
- 抗原
- Nischarin (NISCH)
- 别名
- NISCH (NISCH 产品)
- 别名
- NISCH antibody, IRAS antibody, 1200007D05Rik antibody, 3202002H23Rik antibody, AW494485 antibody, I-1 antibody, IR1 antibody, hIRAS antibody, nischarin antibody, nischarin S homeolog antibody, NISCH antibody, Cyan7822_6841 antibody, nisch.S antibody, nisch antibody, Nisch antibody
- 背景
- Background: Nischarin (NISCH) is a nonadrenergic imidazoline-1 receptor protein that localizes to the cytosol and anchors to the inner layer of the plasma membrane. The orthologous mouse protein has been shown to influence cytoskeletal organization and cell migration by binding to alpha-5-beta-1 integrin. In humans, this protein has been shown to bind to the adapter insulin receptor substrate 4 (IRS4) to mediate translocation of alpha-5 integrin from the cell membrane to endosomes. Expression of NISCH was reduced in human breast cancers while its overexpression reduced tumor growth and metastasis, possibly by limiting the expression of alpha-5 integrin. In human cardiac tissue, this gene was found to affect cell growth and death while in neural tissue it affected neuronal growth and differentiation[taken from NCBI Entrez Gene (Gene ID: 11188)].
- 基因ID
- 11188
- UniProt
- Q9Y2I1
-
