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- 抗原 See all ADD2 抗体
- ADD2 (Adducin 2 (Beta) (ADD2))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 产品特性
- Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human ADD2.
- 亚型
- IgG
- Top Product
- Discover our top product ADD2 Primary Antibody
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anti-Adducin 2 (Beta) (ADD2) (Internal Region) antibody
ADD2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (Internal Region) antibodyADD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (AA 1-726) antibodyADD2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (Internal Region) antibodyADD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (AA 401-500) antibodyADD2 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) antibodyADD2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (AA 648-697) antibodyADD2 适用: 人, Cow, 马, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (AA 1-726) antibodyADD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) (Middle Region) antibodyADD2 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 豚鼠, 兔 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adducin 2 (Beta) (ADD2) antibodyADD2 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C.
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- 抗原
- ADD2 (Adducin 2 (Beta) (ADD2))
- 别名
- ADD2 (ADD2 产品)
- 别名
- si:dkey-202n14.5 antibody, ADDB antibody, 2900072M03Rik antibody, add97 antibody, beta-ADD antibody, adducin 2 antibody, adducin 2 (beta) antibody, ADD2 antibody, add2 antibody, Add2 antibody
- 基因ID
- 119
- UniProt
- P35612
- 途径
- Regulation of Actin Filament Polymerization
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