ADD2 产品
(Adducin 2 (Beta) (ADD2))
Categories
Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010].
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Featured ADD2 Categories
ADD2 抗体
High quality antibodies with extensive validation data.
ADD2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
ADD2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ADD2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7185800
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF
Validations
- (2)
Cat. No.
ABIN3183187
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN947536
Quantity
100 μL
Datasheet
Datasheet
Recommended ADD2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380906
Quantity
96 tests
Datasheet
Datasheet
Recommended ADD2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305969
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3088423
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3130516
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to ADD2
adducin 2 (ADD2), adducin 2 (beta) (add2), adducin 2 (add2), adducin 2 (beta) (Add2), adducin 2 (Add2), 2900072M03Rik, add97, ADDB, beta-ADD, si:dkey-202n14.5Protein level used designations for ADD2
- adducin 2 (beta)
- beta-adducin
- erythrocyte adducin subunit beta
- beta-adducin-like
- snoRNA MBII-396
- adducin beta
- adducin-63
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