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ADCY5 产品

(Adenylate Cyclase 5 (ADCY5))
This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].

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Featured ADCY5 Categories

ADCY5 抗体

High quality antibodies with extensive validation data.

ADCY5 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

ADCY5 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ADCY5 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN513118
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
  • (2)
Cat. No. ABIN751183
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7238498
Quantity 200 μL
Datasheet Datasheet

Recommended ADCY5 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953495
Quantity 96 tests
Datasheet Datasheet

Recommended ADCY5 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305955
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3111295
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
Cat. No. ABIN3121099
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ADCY5 Products

Oh, Hwang, Lee, Choi, Kim, Kim, Sadovsky, Roh: "Isolation of basal membrane proteins from BeWo cells and their expression in placentas from fetal growth-restricted pregnancies." in: Placenta, Vol. 39, pp. 24-32, (2016) (PubMed).

del Puerto, Díaz-Hernández, Tapia, Gomez-Villafuertes, Benitez, Zhang, Miras-Portugal, Wandosell, Díaz-Hernández, Garrido: "Adenylate cyclase 5 coordinates the action of ADP, P2Y1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation." in: Journal of cell science, Vol. 125, Issue Pt 1, pp. 176-88, (2012) (PubMed).

Drescher, Cho, Folbe, Selvakumar, Kewson, Abu-Hamdan, Oh, Ramakrishnan, Hatfield, Khan, Anne, Harpool, Drescher: "An adenylyl cyclase signaling pathway predicts direct dopaminergic input to vestibular hair cells." in: Neuroscience, Vol. 171, Issue 4, pp. 1054-74, (2010) (PubMed).

Lefkimmiatis, Srikanthan, Maiellaro, Moyer, Curci, Hofer: "Store-operated cyclic AMP signalling mediated by STIM1." in: Nature cell biology, Vol. 11, Issue 4, pp. 433-42, (2009) (PubMed).

Ortiz-Capisano, Ortiz, Harding, Garvin, Beierwaltes: "Adenylyl cyclase isoform v mediates renin release from juxtaglomerular cells." in: Hypertension (Dallas, Tex. : 1979), Vol. 49, Issue 3, pp. 618-24, (2007) (PubMed).

Grünberger, Obermayer, Klar, Kurtz, Schweda: "The calcium paradoxon of renin release: calcium suppresses renin exocytosis by inhibition of calcium-dependent adenylate cyclases AC5 and AC6." in: Circulation research, Vol. 99, Issue 11, pp. 1197-206, (2006) (PubMed).

Kolachala, Asamoah, Wang, Srinivasan, Merlin, Sitaraman: "Interferon-gamma down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase." in: The Journal of biological chemistry, Vol. 280, Issue 6, pp. 4048-57, (2005) (PubMed).

Ding, Gros, Gray, Taussig, Ferguson, Feldman: "Raf kinase activation of adenylyl cyclases: isoform-selective regulation." in: Molecular pharmacology, Vol. 66, Issue 4, pp. 921-8, (2004) (PubMed).

Wicker, Catalan, Cailleux, Starenki, Stengel, Sarasin, Suarez: "Cloning and expression of human adenylyl cyclase type VI in normal thyroid tissues." in: Biochimica et biophysica acta, Vol. 1493, Issue 1-2, pp. 279-83, (2000) (PubMed).

Hellevuo, Yoshimura, Kao, Hoffman, Cooper, Tabakoff: "A novel adenylyl cyclase sequence cloned from the human erythroleukemia cell line." in: Biochemical and biophysical research communications, Vol. 192, Issue 1, pp. 311-8, (1993) (PubMed).

Synonyms and alternative names related to ADCY5

adenylate cyclase 5 (ADCY5), adenylate cyclase 5 (adcy5), adenylate cyclase 5 (Adcy5), AC5, Ac5, ADCY5, AW121902, FDFM, RUT, si:dkeyp-60a7.2

Protein level used designations for ADCY5

  • adenylate cyclase type 5
  • adenylyl cyclase type V
  • adenylate cyclase 5
  • ac5
  • fan
  • fantasma
  • ATP pyrophosphate-lyase 5
  • adenylate cyclase type V
  • adenylyl cyclase 5
  • ca(2+)-inhibitable adenylyl cyclase
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