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ADD2 蛋白

(Adducin 2 (Beta) (ADD2))
Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010].
ADD2 Protein (AA 1-726) (GST tag) ADD2 Protein (AA 1-726) (GST tag) ADD2 Protein (AA 1-726) (GST tag) (ABIN1305969)

ADD2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

ADD2 Protein (AA 1-726) (His tag) ADD2 Protein (AA 1-726) (His tag) ADD2 Protein (AA 1-726) (His tag) (ABIN3088423)

Crystallography grade ADD2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

ADD2 Protein (AA 2-725) (His tag) ADD2 Protein (AA 2-725) (His tag) ADD2 Protein (AA 2-725) (His tag) (ABIN3130516)

Crystallography grade ADD2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

ADD2 蛋白 by Grade

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ADD2 蛋白 by Origin

Find ADD2 蛋白 for a variety of species such as anti-Human ADD2, anti-Mouse ADD2, anti-Rat ADD2. The species listed below are among those available. Click on a link to go to the corresponding products.

ADD2 蛋白 by Source

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ADD2 蛋白 by 蛋白类型

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ADD2 蛋白 by 应用范围

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Popular ADD2 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305969
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3088423
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3130516
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2715230
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1473793
Quantity 1 mg
Datasheet Datasheet

Aliases for ADD2 蛋白

adducin 2 (ADD2) 蛋白
adducin 2 (beta) (add2) 蛋白
adducin 2 (add2) 蛋白
adducin 2 (beta) (Add2) 蛋白
adducin 2 (Add2) 蛋白
2900072M03Rik 蛋白
add97 蛋白
ADDB 蛋白
beta-ADD 蛋白
si:dkey-202n14.5 蛋白
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