RAD51 抗体
Quick Overview for RAD51 抗体 (ABIN4902204)
抗原
See all RAD51 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Rad51 is a protein encoded by the RAD51 gene which is approximately 35 kDa. Rad51 is localised to the nucleus, cytoplasm and mitochondrion matirx. It is involved in the resolution of D-loop structures through synthesis-dependent strand annealing, DNA double-strand break repair, ATM pathway and the BRCA1 pathway. It is known to be involved in the homologous strand exchange, a key step in DNA repair through homologous recombination and repair of DNA. It catalyses the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Rad51 is highly expressed in the testis and thymus and less expressed in the small intestine, placenta, colon, pancreas and ovary. Mutations in the RAD51 gene result in breast cancer and Fanconi anemia, a disorder affecting all bone marrow elements. STJ99103 was developed from clone 4H10-G5-H4. It was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and detects endogenous levels of Rad51 and does not cross-react with related proteins.
-
特异性
- This antibody detects endogenous levels of Rad51 and does not cross-react with related proteins.
-
产品特性
- Mouse Monoclonal to Rad51.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Recombinant peptide derived from human Rad51.
-
亚型
- IgG2a
-
-
anti-DNA Repair Protein Homolog 1 (RAD51) (AA 1-339) antibody
RAD51 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) (Center) antibodyRAD51 适用: 人, 小鼠 WB, IP, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) (AA 81-180) antibodyRAD51 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) (AA 1-228) antibodyRAD51 适用: 人 WB, ELISA, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) (AA 1-339) antibodyRAD51 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) (AA 1-242) antibodyRAD51 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E5-E5 unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) (AA 1-134) antibodyRAD51 适用: 人 IHC, FACS, ISt, StM 宿主: 小鼠 Monoclonal RAD51-2702 unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) (AA 1-134) antibodyRAD51 适用: 人 WB, IHC, FACS, ISt, StM 宿主: 小鼠 Monoclonal RAD51-2701 unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) (AA 1-242) antibodyRAD51 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4C11-B4 unconjugated
anti-DNA Repair Protein Homolog 1 (RAD51) antibodyRAD51 适用: 人, 小鼠 WB, ELISA, IP, IF 宿主: 小鸡 Polyclonal unconjugated
-
-
应用备注
-
WB 1:500-2000
ELISA 1:10000-20000 -
说明
-
Highly expressed in testis and thymus, followed by small intestine, placenta, colon, pancreas and ovary. Weakly expressed in breast.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze/thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
-
-
- RAD51 (DNA Repair Protein Homolog 1 (RAD51))
-
别名
- Rad51
-
分子量
- 37kDa
-
基因ID
- 5888
-
UniProt
- Q06609
-
途径
- DNA Damage Repair
抗原
-
