MLKL 抗体 (pSer358)
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- 抗原 See all MLKL 抗体
- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
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抗原表位
- pSer358
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MLKL antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- MLKL is a protein encoded by the MLKL gene which is approximately 54,4 kDa. MLKL is localised to the cell membrane and cytoplasm. It is involved in the dimerization of procaspase-8, the TNF signalling pathway, apoptosis and autophagy. This protein falls under the protein kinase superfamily. It plays a critical role in tumour necrosis factor-induced necroptosis which is a programmed cell death process. It does this via interaction with the receptor-interacting protein 3 which is a key signalling molecule in necroptosis pathway. MLKL is expressed in the heart, intestine and lung. STJ97776 was developed from clone 6F8 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen MLKL. This primary antibody specifically binds to endogenous MLKL protein which only binds about S358 when S358 is phosphorylated.
- 特异性
- Phospho-MLKL (S358) Mouse Monoclonal Antibody (6F8) detects endogenous levels of MLKL
- 产品特性
- Mouse Monoclonal to phospho-MLKL (S358).
- 纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
- 免疫原
- synthetic peptide derived from phospho-MLKL (S358)
- 克隆位点
- 6F8
- 亚型
- IgG1
- Top Product
- Discover our top product MLKL Primary Antibody
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anti-Mixed Lineage Kinase Domain-Like (MLKL) antibody
MLKL 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 371-471) antibodyMLKL 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3B2 unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (Internal Region) antibodyMLKL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 444-472) antibodyMLKL 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 1-471) antibodyMLKL 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (C-Term) antibodyMLKL 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (pSer358) antibodyMLKL 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal 6E3 unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyMLKL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 371-472) antibodyMLKL 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3B2 unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyMLKL 适用: 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC 1:100-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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