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Lamin A/C 抗体

This anti-Lamin A/C antibody is a 小鼠 单克隆 antibody detecting Lamin A/C in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN4901871
发货至: 中国

Quick Overview for Lamin A/C 抗体 (ABIN4901871)

抗原

See all Lamin A/C (LMNA) 抗体
Lamin A/C (LMNA)

适用

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人, 小鼠, 大鼠

宿主

  • 112
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  • 2
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小鼠

克隆类型

  • 110
  • 52
单克隆

标记

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This Lamin A/C antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

4E7
  • 原理

    Mouse monoclonal to Lamin A.

    特异性

    Lamin A Monoclonal Antibody detects endogenous levels of Lamin A protein.

    产品特性

    Mouse Monoclonal to Lamin A.

    纯化方法

    Affinity purification

    免疫原

    Purified recombinant fragment of human Lamin A expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    WB 1:500-1:2000
    IHC 1:200-1:1000
    ELISA 1:10000

    说明

    In the arteries, prelamin-A/C accumulation is not observed in young healthy vessels but is prevalent in medial vascular smooth muscle cells (VSMCs) from aged individuals and in atherosclerotic lesions, where it often colocalizes with senescent and degenerate VSMCs. Prelamin-A/C expression increases with age and disease. In normal aging, the accumulation of prelamin-A/C is caused in part by the down-regulation of ZMPSTE24/FACE1 in response to oxidative stress.

    限制

    仅限研究用
  • 缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原

    Lamin A/C (LMNA)

    别名

    Lamin A

    基因ID

    4000

    UniProt

    P02545

    途径

    Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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