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Collagen IV 抗体

This 小鼠 单克隆 anti-Collagen IV antibody specifically detects Collagen IV in IHC 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN4901302
发货至: 中国
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Quick Overview for Collagen IV 抗体 (ABIN4901302)

抗原

See all Collagen IV (COL4) 抗体
Collagen IV (COL4) (Collagen, Type IV (COL4))

适用

  • 96
  • 47
  • 39
  • 22
  • 17
  • 12
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 64
  • 28
  • 12
小鼠

克隆类型

  • 74
  • 30
单克隆

标记

  • 48
  • 10
  • 7
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Collagen IV antibody is un-conjugated

应用范围

  • 63
  • 48
  • 33
  • 32
  • 30
  • 26
  • 26
  • 25
  • 15
  • 11
  • 9
  • 8
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    Collagen IV is a protein encoded by the COL4A1 gene which is approximately 160,6 kDa. Collagen IV is secreted into the extracellular space. It is involved in collagen chain trimerization, the integrin pathway, ERK signalling and focal adhesion. It is the major structural component of glomerular basement membranes and forms a chicken-wire meshwork together with laminins, proteoglycans and entactin/nidogen. It specifically inhibits endothelial cell proliferation, migration and tube formation. Collagen IV is expressed in the nervous system, liver, lung, heart and kidney. Mutations in the COL4A1 gene may result in the tortuosity of retinal arteries. STJ98907 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous Collagen IV protein.

    特异性

    The antibody detects endogenous Collagen IV protein.

    产品特性

    Mouse Monoclonal to Collagen IV.

    纯化方法

    The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    synthetic peptide derived from Collagen IV.
  • 应用备注

    IF 1:50-200
    IHC-P 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原

    Collagen IV (COL4) (Collagen, Type IV (COL4))

    别名

    Collagen IV

    分子量

    161kDa

    UniProt

    P02462
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