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Histone 3 抗体 (H3K36me2)

This anti-Histone 3 antibody is a 兔 多克隆 antibody detecting Histone 3 in WB, IF, ChIP, DB, ICC 和 ChIP-seq. Suitable for 人 和 Saccharomyces cerevisiae. This Primary Antibody has been cited in 8+ publications.
产品编号 ABIN4889654
发货至: 中国

Quick Overview for Histone 3 抗体 (H3K36me2) (ABIN4889654)

抗原

See all Histone 3 (H3) 抗体
Histone 3 (H3) (Histone H3 (H3))

适用

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人, Saccharomyces cerevisiae

宿主

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克隆类型

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多克隆

标记

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This Histone 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB), Immunocytochemistry (ICC), ChIP DNA-Sequencing (ChIP-seq)
  • 抗原表位

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    H3K36me2

    纯化方法

    None

    免疫原

    This Histone H3 dimethylLys36 antibody was raised against a peptide including dimethyllysine 36 of histone H3.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    储存条件

    -20 °C

    储存方法

    Antibodies in solution can be stored at -20 °C for 2 years.

    有效期

    6 months
  • Young, Hillyer, Hokamp, Fitzpatrick, Konstantinov, Welty, Ness, Werner-Washburne, Fleming, Osley: "Distinct histone methylation and transcription profiles are established during the development of cellular quiescence in yeast." in: BMC genomics, Vol. 18, Issue 1, pp. 107, (2017) (PubMed).

    García-Carpizo, Sarmentero, Han, Graña, Ruiz-Llorente, Pisano, Serrano, Brooks, Campbell, Barrero: "NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation." in: Scientific reports, Vol. 6, pp. 32952, (2016) (PubMed).

    Luense, Denner, Fernández-Montalván, Hartung, Husemann, Stresemann, Prechtl: "Quantification of histone H3 Lys27 trimethylation (H3K27me3) by high-throughput microscopy enables cellular large-scale screening for small-molecule EZH2 inhibitors." in: Journal of biomolecular screening, Vol. 20, Issue 2, pp. 190-201, (2015) (PubMed).

    Feng, Zhang, Shea, Creighton, Coarfa, Hilsenbeck, Lanz, He, Wang, Fu, Nardone, Song, Bradner, Mitsiades, Mitsiades, Osborne, Schiff, OMalley: "An epigenomic approach to therapy for tamoxifen-resistant breast cancer." in: Cell research, Vol. 24, Issue 7, pp. 809-19, (2014) (PubMed).

    Jha, Strahl: "An RNA polymerase II-coupled function for histone H3K36 methylation in checkpoint activation and DSB repair." in: Nature communications, Vol. 5, pp. 3965, (2014) (PubMed).

    Ma, Pan, Montgomery, Olson, Schultz: "Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 8, pp. E481-9, (2012) (PubMed).

    Hainer, Martens: "Identification of histone mutants that are defective for transcription-coupled nucleosome occupancy." in: Molecular and cellular biology, Vol. 31, Issue 17, pp. 3557-68, (2011) (PubMed).

    Hsia, Tepper, Pochampalli, Hsia, Izumiya, Huerta, Wright, Chen, Kung, Izumiya: "KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 21, pp. 9671-6, (2010) (PubMed).

  • 抗原

    Histone 3 (H3) (Histone H3 (H3))

    别名

    Histone H3

    分子量

    17 kDa

    基因ID

    3020
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