HACE1 抗体 (Internal Region)
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- 抗原 See all HACE1 抗体
- HACE1 (HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 非洲爪蟾
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HACE1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
- 特异性
- Reacts with human 102 kDa HACE1 protein
- 交叉反应
- 小鼠
- 交叉反应 （详细）
- Cross react with mouse and Xenopus protein due to sequence homology.
- 纯化方法
- Purified (protein A)
- 免疫原
- Synthetic peptide derived from internal domain ofhuman HACE1 protein.
- Top Product
- Discover our top product HACE1 Primary Antibody
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anti-HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) antibody
HACE1 适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) (AA 1-100) antibodyHACE1 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) (AA 75-170) antibodyHACE1 适用: 小鼠 ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) (AA 333-442) antibodyHACE1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) antibodyHACE1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) (C-Term) antibodyHACE1 适用: 人, 小鼠, 大鼠 ELISA, IHC, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) antibodyHACE1 适用: 人 WB 宿主: 小鼠 Monoclonal 1854CT757-66-47 unconjugated
anti-HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) (AA 800-909) antibodyHACE1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) (AA 792-841) antibodyHACE1 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, Cow, 犬, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) (Middle Region) antibodyHACE1 适用: 人, 小鼠, 大鼠, 兔, 豚鼠, Cow, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB: 1/1000 to 1/5000 IHC: 1/100 to 1/1000 - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Must be reconstituted in distilled water.
- 浓度
- 1 mg/mL
- 缓冲液
- Tris 0,1M, glycine 0,1M, sucrose 2 %
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- 有效期
- 24 months
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- 抗原
- HACE1 (HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1))
- 别名
- E3 Ubiquitin-Protein Ligase HACE1 (HACE1 产品)
- 别名
- HACE1 antibody, 1700042J16Rik antibody, A730034A22Rik antibody, BC025474 antibody, HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 antibody, HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 L homeolog antibody, HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 antibody, HACE1 antibody, hace1 antibody, hace1.L antibody, Hace1 antibody
- 背景
- E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.
- 基因ID
- 57531
- UniProt
- Q8IYU2
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