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- 抗原 See all RECQL2 (WRN) 抗体
- RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))
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抗原表位
- AA 122-240
- 适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RECQL2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Werner syndrome ATP-dependent helicase(WRN) detection. Tested with WB in Human,Rat.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Werner syndrome ATP-dependent helicase(WRN) detection. Tested with WB in Human,Rat.
Gene Name: Werner syndrome RecQ like helicase
Protein Name: Werner syndrome ATP-dependent helicase - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived human WRN recombinant protein (Position: Q122-N240). Human WRN shares 84% amino acid (aa) sequence identity with mouse WRN.
- 亚型
- IgG
- Top Product
- Discover our top product WRN Primary Antibody
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anti-Werner syndrome RecQ like helicase (WRN) (AA 1322-1432) antibody
WRN 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C11 unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (Internal Region) antibodyWRN 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (Center) antibodyWRN 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Werner syndrome RecQ like helicase (WRN) antibodyWRN 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal 195C unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (AA 787-816) antibodyWRN 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17383 unconjugated
anti-Werner syndrome RecQ like helicase (WRN) antibodyWRN 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (AA 1322-1432) antibodyWRN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F7 unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (AA 1322-1432) antibodyWRN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (AA 1223-1432) antibodyWRN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Werner syndrome RecQ like helicase (WRN) (AA 794-825), (Middle Region), (Thr802) antibodyWRN 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))
- 别名
- WRN (WRN 产品)
- 背景
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Werner syndrome ATP-dependent helicase, also known as DNA helicase, RecQ-like type 3, is an enzyme that in humans is encoded by the WRN gene. This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.
Synonyms: Exonuclease WRN | RecQ3 | RECQL2 | RECQL3 | WRN | Q14191 - 基因ID
- 7486
- UniProt
- Q14191
- 途径
- DNA Damage Repair
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