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APC2 抗体 (N-Term)

APC2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4886464
发货至: 中国
  • 抗原 See all APC2 抗体
    APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))
    抗原表位
    • 15
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    AA 51-90, N-Term
    适用
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    宿主
    • 27
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    克隆类型
    • 27
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    多克隆
    标记
    • 11
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    This APC2 antibody is un-conjugated
    应用范围
    • 13
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    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Adenomatous polyposis coli protein 2(APC2) detection. Tested with WB in Human.
    序列
    KHLQGKLEQE ARVLVSSGQT EVLEQLKALQ MDITSLYNLK
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Adenomatous polyposis coli protein 2(APC2) detection. Tested with WB in Human.
    Gene Name: APC2, WNT signaling pathway regulator
    Protein Name: Adenomatous polyposis coli protein 2
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human APC2 (51-90aa KHLQGKLEQEARVLVSSGQTEVLEQLKALQMDITSLYNLK), different from the related mouse sequence by two amino acids.
    亚型
    IgG
    Top Product
    Discover our top product APC2 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    APC2 (APC Regulator of WNT Signaling Pathway 2 (APC2))
    别名
    APC2 (APC2 产品)
    别名
    APCL antibody, AI852447 antibody, R75424 antibody, APC2, WNT signaling pathway regulator antibody, adenomatosis polyposis coli 2 antibody, APC2 antibody, Apc2 antibody
    背景
    APC2, which is also called APCL, is a deduced 2,303-amino acid protein that contains an N-terminal coiled-coil domain, followed by an armadillo domain and five 20-amino acid repeats. The human APC2 gene is mapped to chromosome 19p13.3. It is found that the 20-amino acid repeat domain of APCL could bind beta-catenin (CTNNB1) and deplete the intracellular beta-catenin pool. A reporter gene assay revealed that APCL could regulate interaction of beta-catenin with T cell-specific transcription factors (TCF7), although less efficiently than APC.

    Synonyms: APCL | APC2 | APC 2 | O95996
    基因ID
    10297
    途径
    WNT signaling
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