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Retinoblastoma 1 抗体 (HRP)

RB1 适用: 人, 小鼠 宿主: 小鼠 Monoclonal 1F8 HRP
产品编号 ABIN4880121
发货至: 中国
  • 抗原 See all Retinoblastoma 1 (RB1) 抗体
    Retinoblastoma 1 (RB1)
    适用
    • 231
    • 105
    • 92
    • 5
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    人, 小鼠
    宿主
    • 205
    • 28
    小鼠
    克隆类型
    • 195
    • 38
    单克隆
    标记
    • 128
    • 8
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    • 2
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    This Retinoblastoma 1 antibody is conjugated to HRP
    应用范围
    请咨询
    特异性
    This antibody recognises retinoblastoma-associated protein (RB), a 105 kDa tumour suppressor which is also known as Rb1. Rb1 functions as a transcription factor that controls cell cycle progression (at the G1/S phase transition) through its repression of E2F-mediated transcription. Mutation of the Rb gene is found frequently in human sarcomas, lung, bladder and breast carcinomas and is the molecular basis for hereditary disposition to retinoblastoma.
    纯化方法
    Purified on protein A from tissue culture supernatant.
    免疫原
    Rb-b-galactosidase fusion protein spanning nucleotides 1126-1973 of human Rb gel purified from bacterial lysates
    克隆位点
    1F8
    亚型
    IgG1
    Top Product
    Discover our top product RB1 Primary Antibody
  • 应用备注
    Optimal antibody dilution should be determined by titration
    说明

    Myeloma, fusion partnersCells from immunized Balb/c mice were fused with the Sp2/0-Ag.14 myeloma cell line

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Purified IgG conjugated to Horseradish Peroxidase using Innova Biosciences Lightning-Link ®, supplied in Phosphate buffered saline (PBS) containing 0.01 % Thiomersal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate) a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    Retinoblastoma 1 (RB1)
    别名
    Rb1 (RB1 产品)
    基因ID
    5925, 19645
    OMIM
    614041
    途径
    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
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