Retinoblastoma 1 抗体 (HRP)
-
- 抗原 See all Retinoblastoma 1 (RB1) 抗体
- Retinoblastoma 1 (RB1)
-
适用
- 人, 小鼠
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This Retinoblastoma 1 antibody is conjugated to HRP
- 应用范围
- 请咨询
- 特异性
- This antibody recognises retinoblastoma-associated protein (RB), a 105 kDa tumour suppressor which is also known as Rb1. Rb1 functions as a transcription factor that controls cell cycle progression (at the G1/S phase transition) through its repression of E2F-mediated transcription. Mutation of the Rb gene is found frequently in human sarcomas, lung, bladder and breast carcinomas and is the molecular basis for hereditary disposition to retinoblastoma.
- 纯化方法
- Purified on protein A from tissue culture supernatant.
- 免疫原
- Rb-b-galactosidase fusion protein spanning nucleotides 1126-1973 of human Rb gel purified from bacterial lysates
- 克隆位点
- 1F8
- 亚型
- IgG1
- Top Product
- Discover our top product RB1 Primary Antibody
-
-
- 应用备注
- Optimal antibody dilution should be determined by titration
- 说明
-
Myeloma, fusion partnersCells from immunized Balb/c mice were fused with the Sp2/0-Ag.14 myeloma cell line
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Purified IgG conjugated to Horseradish Peroxidase using Innova Biosciences Lightning-Link ®, supplied in Phosphate buffered saline (PBS) containing 0.01 % Thiomersal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate) a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
- 抗原
- Retinoblastoma 1 (RB1)
- 别名
- Rb1 (RB1 产品)
- 基因ID
- 5925, 19645
- OMIM
- 614041
- 途径
- Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagy
-