ELOVL4 抗体
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- 抗原 See all ELOVL4 抗体
- ELOVL4 (ELOVL Fatty Acid Elongase 4 (ELOVL4))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ELOVL4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- This antibody detects ELOV4, expressed in the retina and at much lower level in the brain.
- 纯化方法
- Affinity chromatography
- 免疫原
- Synthetic peptdide derived from the human ELOV4 protein
- 亚型
- IgG
- Top Product
- Discover our top product ELOVL4 Primary Antibody
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anti-ELOVL Fatty Acid Elongase 4 (ELOVL4) (AA 270-314) antibody
ELOVL4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ELOVL Fatty Acid Elongase 4 (ELOVL4) (AA 1-100) antibodyELOVL4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-ELOVL Fatty Acid Elongase 4 (ELOVL4) (Internal Region) antibodyELOVL4 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ELOVL Fatty Acid Elongase 4 (ELOVL4) (Internal Region) antibodyELOVL4 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-ELOVL Fatty Acid Elongase 4 (ELOVL4) (AA 286-314), (C-Term) antibodyELOVL4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Blot (1: 400 starting dilution).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- Phosphate buffered saline with 0.08 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
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- 抗原
- ELOVL4 (ELOVL Fatty Acid Elongase 4 (ELOVL4))
- 别名
- ELOVL4 (ELOVL4 产品)
- 别名
- elovl4 antibody, MGC122553 antibody, ADMD antibody, CT118 antibody, ISQMR antibody, STGD2 antibody, STGD3 antibody, elongation of very long chain fatty acids protein 4 antibody, ELOVL fatty acid elongase 4 antibody, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4 antibody, CpipJ_CPIJ002114 antibody, CpipJ_CPIJ003687 antibody, CpipJ_CPIJ011025 antibody, CpipJ_CPIJ013819 antibody, ELOVL4 antibody, elovl4 antibody, Elovl4 antibody
- 背景
- Mutations in elongation of very long-chain fatty acid-4 (ELOVL4) are associated with autosomal dominant Stargardt-like macular degeneration (STGD3), with a five base-pair (5 bp) deletion mutation resulting in the loss of 51 carboxy-terminal amino acids and truncation of the protein. Elovl4 is expressed in the retina and only a limited number of mammalian other tissues, including skin, with unknown function. In a mouse model with the 5-bp deletion in the Elovl4 gene, mice in the heterozygous state (Elovl4(+/del)) demonstrate progressive photoreceptor degeneration. Homozygous mice (Elovl4(del/del)) display scaly, wrinkled skin, have severely compromised epidermal permeability barrier function, and die within a few hours after birth. Lipid analyses of epidermis from Elovl4(del/del) mice show a decrease in very long-chain fatty acids (VLFAs) in both the ceramide/glucosylceramide and the free fatty-acid fractions. ELOVL4 is required for generating VLFA critical for epidermal barrier function.Synonyms: 3-keto acyl-CoA synthase ELOVL4, Elongation of very long chain fatty acids protein 4
- 基因ID
- 6785
- NCBI登录号
- NP_073563
- UniProt
- Q9GZR5
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