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- 抗原 See all SREBF1 抗体
- SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SREBF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to SREBF1.
- 纯化方法
- Affinity chromatography on Protein A
- 免疫原
- KLH conjugated synthetic peptide selected from the Center region of human SREBF1
- Top Product
- Discover our top product SREBF1 Primary Antibody
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anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 38-201) antibody
SREBF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 801-900) antibodySREBF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B10 unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (pSer439) antibodySREBF1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 1-100) antibodySREBF1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 349-378) antibodySREBF1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB21265 unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (Middle Region) antibodySREBF1 适用: 人, 大鼠, 小鼠, Cow, 山羊, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 158-390) antibodySREBF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (Tyr1175) antibodySREBF1 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 461-510) antibodySREBF1 适用: 人, 大鼠, Hamster, Cow, 山羊, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) (AA 250-330) antibodySREBF1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
- 别名
- SREBF1 / SREBP1 (SREBF1 产品)
- 别名
- SREBP-1c antibody, SREBP1 antibody, bHLHd1 antibody, ADD-1 antibody, ADD1 antibody, D630008H06 antibody, SREBP-1 antibody, SREBP-1a antibody, SREBP1c antibody, Srebp1 antibody, SCREBP1 antibody, SREBP-1C antibody, SREBF1 antibody, srebp1 antibody, sterol regulatory element binding transcription factor 1 antibody, sterol regulatory element binding transcription factor 1 L homeolog antibody, sterol regulatory element binding protein-1 antibody, Sterol regulatory element Binding Protein antibody, SREBF1 antibody, Srebf1 antibody, srebf1.L antibody, SREBP-1 antibody, srebf1 antibody, sbp-1 antibody
- 背景
- SREBF1 is a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family.Synonyms: BHLHD1, Class D basic helix-loop-helix protein 1, SREBP-1, Sterol regulatory element-binding protein 1, Sterol regulatory element-binding transcription factor 1
- 基因ID
- 6720
- NCBI登录号
- NP_001005291
- UniProt
- P36956
- 途径
- AMPK Signaling, Caspase Cascade in Apoptosis, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
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