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SREBF1 抗体 (AA 349-378)
SREBF1
适用: 人
WB, IHC (p), FACS
宿主: 兔
Polyclonal
RB21265
unconjugated
SREBF1抗体详情
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抗原
See all SREBF1 抗体
SREBF1
(Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
抗原表位
All epitopes for SREBF1 抗体
AA 349-378
适用
All reactivities for SREBF1 抗体
人
宿主
All hosts for SREBF1 抗体
兔
克隆类型
All clonalities for SREBF1 抗体
多克隆
标记
All conjugates for SREBF1 抗体
This SREBF1 antibody is un-conjugated
应用范围
All applications for SREBF1 抗体
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
预测反应
Ha, M, Rat
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This SREBF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349-378 amino acids of human SREBF1.
克隆位点
RB21265
亚型
IgG
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使用细节
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应用备注
WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期
6 months
SREBF1目标详情
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抗原
SREBF1
(Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1))
别名
SREBF1 (SREBF1 产品 )
别名
SREBP-1c antibody, SREBP1 antibody, bHLHd1 antibody, ADD-1 antibody, ADD1 antibody, D630008H06 antibody, SREBP-1 antibody, SREBP-1a antibody, SREBP1c antibody, Srebp1 antibody, SCREBP1 antibody, SREBP-1C antibody, SREBF1 antibody, srebp1 antibody, sterol regulatory element binding transcription factor 1 antibody, sterol regulatory element binding transcription factor 1 L homeolog antibody, sterol regulatory element binding protein-1 antibody, Sterol regulatory element Binding Protein antibody, SREBF1 antibody, Srebf1 antibody, srebf1.L antibody, SREBP-1 antibody, srebf1 antibody, sbp-1 antibody
背景
SREBF1 is a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor, and the mature nuclear form is rapidly catabolized, thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family.
分子量
121675
基因ID
6720
NCBI登录号
NP_001005291 , NP_004167
UniProt
P36956
途径
AMPK Signaling , Caspase Cascade in Apoptosis , Negative Regulation of Hormone Secretion , Regulation of Lipid Metabolism by PPARalpha
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