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Ghrelin 抗体 (C-Term)

GHRL 适用: 人, 大鼠 IHC (p), EIA, IF 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN452691
发货至: 中国
  • 抗原 See all Ghrelin (GHRL) 抗体
    Ghrelin (GHRL)
    抗原表位
    • 16
    • 15
    • 9
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 80
    • 52
    • 24
    • 3
    • 2
    • 1
    人, 大鼠
    宿主
    • 80
    • 18
    • 6
    • 1
    • 1
    山羊
    克隆类型
    • 89
    • 17
    多克隆
    标记
    • 48
    • 9
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Ghrelin antibody is un-conjugated
    应用范围
    • 63
    • 51
    • 26
    • 26
    • 24
    • 12
    • 11
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunofluorescence (IF)
    特异性
    This antibody is expected to recognise all reported isoforms.
    交叉反应 (详细)
    Species reactivity (tested):Human, Rat.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide with sequence C-QDILWEEAKEAPADK, from the C Terminus of the protein sequence according to NP_057446.1, NP_001128413.1, NP_001128416.1, NP_001128417.1, NP_001128418.1.
    Top Product
    Discover our top product GHRL Primary Antibody
  • 应用备注
    Peptide ELISA: Detection Limit: 1/8000. Immunohistochemistry: 2-5 μg/mL. In paraffin embedded Human Placenta shows stainingof trophoblast cytoplasm.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    Ghrelin (GHRL)
    别名
    Ghrelin / GHRL (GHRL 产品)
    别名
    2210006E23Rik antibody, Ghr antibody, MTLRP antibody, MTLRPAP antibody, m46 antibody, Gh1-1 antibody, GRHL antibody, MTLRP-AP antibody, GHR antibody, ghrelin antibody, ghrelin and obestatin prepropeptide antibody, ghrelin/obestatin prepropeptide antibody, Ghrl antibody, GHRL antibody, ghrl antibody
    背景
    Ghrelin was originally discovered as a preprohormone that stimulates the release of growth hormone from the anterior pituitary. Recent studies have shown that ghrelin, in concert with other hormones, helps to control both appetite and energy balance. The synthesis of Ghrelin takes place predominantly in epithelial cells of the stomach, although it is also produced in smaller quantities in the placenta, kidney, pituitary and hypothalamus. Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release from the pituitary. It has an appetite stimulating effect, induces adiposity, and stimulates gastric acid secretion, and it is involved in growth regulation. Ghrelin is synthesized as a preprohormone (13 kDa), then proteolytically processed to yield a 28 amino acid peptide (3 kDa). Obestatin, an appetite suppressing peptide hormone, is also produced in the process. An interesting and unique modification is imposed on the ghrelin hormone during synthesis in the form of octanoic acid bound to one of its amino acids. This modification is necessary for biological activity.Synonyms: Appetite-regulating hormone, Ghrelin-27, Ghrelin-28, Growth hormone secretagogue, Growth hormone-releasing peptide, M46 protein, MTLRP, Motilin-related peptide, Obestatin
    基因ID
    51738
    NCBI登录号
    NP_001128413
    UniProt
    Q9UBU3
    途径
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Negative Regulation of Hormone Secretion, Synaptic Membrane, Feeding Behaviour
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