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Ghrelin 抗体 (AA 1-117)

GHRL 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6141079
发货至: 中国
  • 抗原 See all Ghrelin (GHRL) 抗体
    Ghrelin (GHRL)
    抗原表位
    • 16
    • 15
    • 9
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-117
    适用
    • 79
    • 52
    • 24
    • 3
    • 2
    • 1
    宿主
    • 79
    • 18
    • 6
    • 1
    • 1
    克隆类型
    • 88
    • 17
    多克隆
    标记
    • 47
    • 9
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Ghrelin antibody is un-conjugated
    应用范围
    • 62
    • 51
    • 26
    • 26
    • 23
    • 12
    • 11
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    MPSPGTVCSL LLLGMLWLDL AMAGSSFLSP EHQRVQQRKE SKKPPAKLQP RALAGWLRPE DGGQAEGAED ELEVRFNAPF DVGIKLSGVQ YQQHSQALGK FLQDILWEEA KEAPADK
    交叉反应
    人, 大鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-117 of human GHRL (NP_057446.1).
    亚型
    IgG
    Top Product
    Discover our top product GHRL Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Ghrelin (GHRL)
    别名
    GHRL (GHRL 产品)
    别名
    2210006E23Rik antibody, Ghr antibody, MTLRP antibody, MTLRPAP antibody, m46 antibody, Gh1-1 antibody, GRHL antibody, MTLRP-AP antibody, GHR antibody, ghrelin antibody, ghrelin and obestatin prepropeptide antibody, ghrelin/obestatin prepropeptide antibody, Ghrl antibody, GHRL antibody, ghrl antibody
    背景
    This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.,GHRL,MTLRP,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Obesity,Neuroscience,Cardiovascular,Blood,Heart,Cardiovascular diseases,Heart disease,GHRL
    分子量
    7 kDa/9 kDa/11 kDa/12 kDa
    基因ID
    51738
    UniProt
    Q9UBU3
    途径
    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Negative Regulation of Hormone Secretion, Synaptic Membrane, Feeding Behaviour
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