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FMR1 抗体 (Internal Region)

FMR1 适用: 人, 大鼠 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN452426
发货至: 中国
  • 抗原 See all FMR1 抗体
    FMR1 (Fragile X Mental Retardation 1 (FMR1))
    抗原表位
    • 15
    • 10
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 116-130, Internal Region
    适用
    • 70
    • 47
    • 36
    • 15
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 58
    • 15
    • 2
    山羊
    克隆类型
    • 51
    • 24
    多克隆
    标记
    • 44
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FMR1 antibody is un-conjugated
    应用范围
    • 68
    • 29
    • 18
    • 15
    • 14
    • 14
    • 10
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    c-NPNKPATKDT FHKIK
    特异性
    This antibody Recognizes FMR1.
    交叉反应 (详细)
    Species reactivity (expected):Rat.
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide with sequence from the internal region of the protein sequence according to NP_002015.1. Genename: FMR1
    Top Product
    Discover our top product FMR1 Primary Antibody
  • 应用备注
    Peptide ELISA: 1/32000. Western blot: Approx 70Da band observed in lysates of cell lines HeLa and Jurkat(calculated MW of 71.2 kDa according to NP_002015.1). Recommended concentration: 0.3 -1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    FMR1 (Fragile X Mental Retardation 1 (FMR1))
    别名
    FMR1 / FMRP (FMR1 产品)
    别名
    AT24755 antibody, BcDNA:GM08679 antibody, CG6203 antibody, Dmel\\CG6203 antibody, EP(3)3517 antibody, FMR antibody, FMR1 antibody, FMRP antibody, FMRp antibody, FXR antibody, Fmrp antibody, cg6203 antibody, dFMR antibody, dFMR1 antibody, dFMRP antibody, dFXR antibody, dFXR1 antibody, dFXRP antibody, dFmr1 antibody, dFmrp antibody, dfmr antibody, dfmr1 antibody, dfxr antibody, dfxr1 antibody, dmfr1 antibody, fmr antibody, fmr1 antibody, FRAXA antibody, POF antibody, POF1 antibody, zFMR1 antibody, Fmr-1 antibody, CG6203 gene product from transcript CG6203-RC antibody, fragile X mental retardation 1 antibody, fragile X mental retardation syndrome 1 antibody, Fmr1 antibody, FMR1 antibody, fmr1 antibody
    背景
    FMRP is a RNA-binding protein that is associated to polysomes and may be involved in the transport of mRNA from the nucleus to the cytoplasm. Defects in FMR1 are the cause of Fragile X syndrome, which is a common genetic disease characterized by moderate to severe mental retardation, macroorchidism, large ears, prominent jaw, and high-pitched, jocular speech. The defect in most fragile X syndrome patients results from an amplification of a CGG repeat region which is directly in front of the coding region.Synonyms: Fragile X mental retardation 1 protein, Protein FMR-1
    基因ID
    2332
    NCBI登录号
    NP_002015
    UniProt
    Q06787
    途径
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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